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The Boise State Broncos usher in a new era under quarterback without Kellen Moore. Moore just so happened to leave Boise State as the all-time winningest quarterback in Division I history.
Last season, the Broncos opened up their season against the Georgia Bulldogs in the Georgia Dome. Boise State knocked off the Bulldogs, getting a big win over the SEC. For the season opener in 2012, it will be a team from the Big Ten conference.
The Michigan State Spartans are also starting a new quarterback under center, after Kirk Cousins departed for the NFL.
Both the Broncos and the Spartans enjoyed successful seasons in 2011, but face similar challenges in 2012.
So how do they stack up against each other?
Oddsmakers are siding with Michigan State, who will get the luxury of playing Boise State at home and not on a neutral field.
The Spartans have been set as touchdown favorites over the Broncos on College Football Opening week betting odds available at Bovada Sportsbook.
Despite losing their quarterback, Michigan State implores one of the top defenses in the country, ranking in the top-10 nationally in terms of points allowed in 2011. The Spartans surrendered just 18 points per game last season.
It is the defense that gives Michigan State the edge of Boise State. The Spartans will need to win by at least eight points to cover the betting line. A win by six points or less, and the victory against the spread goes the way of the Broncos.
The over/under total for the game has been set at 45.5 points.
This match up headlines the games on Friday night, kicking off at 8pm ET, with national coverage picked up by ESPN.
There are only two games in the opening weekend between ranked teams, with this being one of them. The other of course is between Alabama and Michigan. Check out the betting odds for this matchup, and the rest on the state below as seen on Bovada.